Nicole Boucheron - Contact & CV

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Nicole Boucheron studied Cellular and Molecular Biology in Strasbourg (France) and Milan (Italy). She pursued her PhD at the Ludwig Institute for Cancer Research, Lausanne Branch (Switzerland) in the group of Immanuel Luescher. She focused on cytotoxic T-cell-activation by soluble peptide-MHC multimers, and was involved in multiple projects, which were published in high impact journals. She graduated at the University of Lausanne in 2002, followed by postdoctoral studies in the group of Wilfried Ellmeier at the Medical University of Vienna, Institute of Immunology. Her work helped to understand important pathways that regulate CD4⁺ T-cell differentiation and she also revealed an unexpected plasticity of CD4⁺ T-cells towards the CD8 lineage. For her work she received the Sanofi Aventis prize (2014). She made also important contributions to other projects in the Ellmeier laboratory, which led to several co-author publications. Since 2018 she established her own research group focusing on the molecular control of T helper cell activation and differentiation during immune responses and disease. Current projects involve molecular determinants for the differentiation of murine and human naïve CD4⁺ T cells into T follicular helper cells and tissue adaptation of Th2 effector cells during allergic airway disease, with a particular interest how class I HDAC inhibition is driving this process. Nicole Boucheron has expertise in the fields of animal disease models, multi-color-flow-cytometry, mouse genetic approaches, advanced primary cell culture techniques, proteomic and high-throughput sequencing.

Curriculum Vitae (download)