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Ellmeier Laboratory

Institute of Immunology

Wilfried Ellmeier / Division of Immunobiology

Our long-term research interest is to characterize molecular mechanisms that regulate the development and function of T lymphocytes. With our studies we aim to provide important and medical relevant insight into the regulation of T cell-mediated immunity. In ongoing studies we address the following research topics:

• The role of histone deacetylases in the regulation of T cell-mediated immunity
• Transcriptional control of T cell development
• Regulation of peripheral T cell function and maintenance of T cell lineage identity and integrity

We are embedded in a strong collaborative environment and the experimental strategies to address our research interests include multi-color flow-cytometry, a variety of immunological tools, biochemical and molecular approaches, retroviral-mediated gene transduction into hematopoietic stem cells, next generation sequencing and mouse molecular genetics tools.

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