Johannes Stöckl / Division of Immune Regulation
Research Focus
We are interested in regulatory mechanisms in adaptive immune responses at the dendritic cell (DC) – T cell interphase. It is our long-term goal to understand how immune cell differentiation and function is regulated by exogenous (human rhino virus, HRV) and endogenous (ct-CD45 and iron) danger signals and to characterize novel and functional relevant receptors on DCs and T cells via which immune responses can be turned on or off. In order to find such regulatory mechanism we are currently investigating the following research topics
As part of the myeloid cell system, DCs are also important for tissue repair and regeneration. We are currently studying the importance of myeloid cells in tendinopathies and are applying our knowledge of immune regulation to new strategies for tendon repair and regeneration.