Publikationen des Instituts für Immunologie
Aktuelle Publikationen
Brinkmann M, Traby L, Kussmann M, Weiss-Tessbach M, Buchtele N, Staudinger T, Gaidoschik E, Perkmann T, Haslacher H, Ratzinger F, Pickl WF, El-Gedawi K, Feichter M, Gelpi E, Höftberger R, Quehenberger P, Marculescu R, Mrak D, Kastrati K, Lechner-Radner H, Sieghart D, Aletaha D, Winkler S, Bonelli M, Göschl L. Autoantibody development is associated with clinical severity of COVID-19: A cohort study. Clin Immunol. 2025 May;274:110471. doi: 10.1016/j.clim.2025.110471. Epub 2025 Mar 3. PMID: 40044018.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40044018/
Arp AB, Abel Gutierrez A, Ter Beest M, Franken GA, Warner H, Rodgers Furones A, Kenyon AN, Jäger F, Cabrera-Orefice A, Kläsener K, van Deventer S, Droesen L, Dunlock VME, Classens R, Staniek J, Borst J, Reth M, Brandt U, Gros P, Kuijpers TW, Heemskerk MHM, Rizzi M, Querol Cano L, van Spriel AB. CD70 recruitment to the immunological synapse is dependent on CD20 in B cells. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2414002122. doi: 10.1073/pnas.2414002122. Epub 2025 Apr 15. PMID: 40232798; PMCID: PMC12037035.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40232798/
Gil-Cantero S, Puck A, Künig S, Pinnarò V, Waidhofer-Söllner P, Stöckl J. The Soluble Cytoplasmic Tail of CD45 (ct-CD45) Regulates Dendritic Cell Activation and Function via TLR4 Signaling. Int J Mol Sci. 2025 Apr 20;26(8):3888. doi: 10.3390/ijms26083888. PMID: 40332754; PMCID: PMC12027817.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40332754/
Mühlgrabner V, Plach A, Holler J, Leitner J, Steinberger P, Dupré L, Göhring J, Huppa JB. Gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Methods Cell Biol. 2025;193:127-154. doi: 10.1016/bs.mcb.2024.03.003. Epub 2024 Apr 15. PMID: 39919839.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39919839/
Zrimšek M, Draganić K, Malzer A, Doblmayr V, Mišura K, de Freitas E Silva R, Matthews JD, Iannelli F, Wohlhaupter S, Pérez Malla CU, Fischer H, Schachner H, Schiefer AI, Sheibani-Tezerji R, Chiarle R, Turner SD, Ellmeier W, Seiser C, Egger G. HDAC1 acts as a tumor suppressor in ALK-positive anaplastic large cell lymphoma: implications for HDAC inhibitor therapy. Leukemia. 2025 Apr 2. doi: 10.1038/s41375-025-02584-9. Epub ahead of print. PMID: 40175628.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40175628/
Voogd L, van den Broek RL, van Wolfswinkel M, Franken KLMC, Ruibal P, Jespers W, Leitner J, Steinberger P, van Westen GJP, Ottenhoff THM, Joosten SA. HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors. J Immunol. 2025 Apr 1;214(4):595-605. doi: 10.1093/jimmun/vkae068. PMID: 40085431; PMCID: PMC12041767.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40085431/
Izadi S, Abrantes R, Gumpelmair S, Kunnummel V, Duarte HO, Steinberger P, Reis CA, Castilho A. An engineered PD1-Fc fusion produced in N. benthamiana plants efficiently blocks PD1/PDL1 interaction. Plant Cell Rep. 2025 Mar 22;44(4):80. doi: 10.1007/s00299-025-03475-0. PMID: 40119938; PMCID: PMC11929711.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40119938/
Farhat A, Radhouani M, Deckert F, Zahalka S, Pimenov L, Fokina A, Hakobyan A, Oberndorfer F, Brösamlen J, Hladik A, Lakovits K, Meng F, Quattrone F, Boon L, Vesely C, Starkl P, Boucheron N, Menche J, van der Veeken J, Ellmeier W, Gorki AD, Campbell C, Gawish R, Knapp S. An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence. Sci Immunol. 2025 Mar 28;10(105):eadk5041. doi: 10.1126/sciimmunol.adk5041. Epub 2025 Mar 28. PMID: 40153488.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40153488/
Wideman SK, Wali L, Kovtunyk V, Chou S, Gusel V, Telimaa H, Najmi C, Stoeva D, Stöckl J, Gualdoni GA, Gorki AD, Radivojev S. Nebulized 2-deoxylated glucose analogues inhibit respiratory viral infection in advanced in vitro airway models. Sci Rep. 2025 Mar 19;15(1):9515. doi: 10.1038/s41598-025-94476-2. PMID: 40108297; PMCID: PMC11923073.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40108297/
Staniek J, Rizzi M. Signaling Activation and Modulation in Extrafollicular B Cell Responses. Immunol Rev. 2025 Mar;330(1):e70004. doi: 10.1111/imr.70004. PMID: 39917832; PMCID: PMC11803499.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39917832/
Khan M, Alteneder M, Reiter W, Krausgruber T, Dobnikar L, Madern M, Waldherr M, Bock C, Hartl M, Ellmeier W, Henriksson J, Boucheron N. Single-cell and chromatin accessibility profiling reveals regulatory programs of pathogenic Th2 cells in allergic asthma. Nat Commun. 2025 Mar 15;16(1):2565. doi: 10.1038/s41467-025-57590-3. PMID: 40089475; PMCID: PMC11910648.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40089475/
Zhu C, Boucheron N, Al-Rubaye O, Chung BK, Thorbjørnsen LW, Köcher T, Schuster M, Claudel T, Halilbasic E, Kunczer V, Muscate F, Cavanagh LL, Waltenberger D, Lercher A, Ohradanova-Repic A, Schatzlmaier P, Stojakovic T, Scharnagl H, Bergthaler A, Stockinger H, Huber S, Bock C, Kenner L, Karlsen TH, Ellmeier W, Trauner M. 24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation. Gut. 2025 Mar 7:gutjnl-2024-333297. doi: 10.1136/gutjnl-2024-333297. Epub ahead of print. PMID: 40032499.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40032499/
Diehl R, Hübner S, Lehr S, Rizzi M, Eyerich K, Nyström A. Skin Deep and Beyond: Unravelling B Cell Extracellular Matrix Interactions in Cutaneous Immunity and Disease. Exp Dermatol. 2025 Mar;34(3):e70068. doi: 10.1111/exd.70068. PMID: 40051023; PMCID: PMC11885703.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40051023/
Tajti G, Gebetsberger L, Pamlitschka G, Aigner-Radakovics K, Leitner J, Steinberger P, Stockinger H, Ohradanova-Repic A. Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8. Front Immunol. 2025 Feb 3;16:1460089. doi: 10.3389/fimmu.2025.1460089. PMID: 39963132; PMCID: PMC11830813.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39963132/