Publikationen

Publikationen des Instituts für Immunologie

Aktuelle Publikationen

Gil-Cantero S, Iorio F, Unalan I, Kurtuldu F, Künig S, Wenhardt C, Pinnaro V, Aigner-Radakovics K, Steinberger P, Boccaccini AR, Stöckl J. Impact of morphological features and chemical composition of tendon biomimetic scaffolds on immune recognition via Toll-like receptors. Biomater Sci. 2024 Jul 31. doi: 10.1039/d4bm00147h. Epub ahead of print. PMID: 39082440.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39082440/

Kratzer B, Gattinger P, Trapin D, Ettel P, Körmöczi U, Rottal A, Stieger RB, Sehgal ANA, Feichter M, Borochova K, Tulaeva I, Grabmeier-Pfistershammer K, Tauber PA, Perkmann T, Fae I, Wenda S, Kundi M, Fischer GF, Valenta R, Pickl WF. Differential decline of SARS-CoV-2-specific antibody levels, innate and adaptive immune cells, and shift of Th1/inflammatory to Th2 serum cytokine levels long after first COVID-19. Allergy. 2024 Jul 14. doi: 10.1111/all.16210. Epub ahead of print. PMID: 39003594.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39003594/

De Sá Fernandes C, Novoszel P, Gastaldi T, Krauß D, Lang M, Rica R, Kutschat AP, Holcmann M, Ellmeier W, Seruggia D, Strobl H, Sibilia M. The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity. Cell Rep. 2024 Jun 25;43(6):114308. doi: 10.1016/j.celrep.2024.114308. Epub 2024 Jun 2. PMID: 38829740.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38829740/

Thiel J, Schmidt FM, Lorenzetti R, Troilo A, Janowska I, Nießen L, Pfeiffer S, Staniek J, Benassini B, Bott MT, Korzhenevich J, Konstantinidis L, Burgbacher F, Dufner AK, Frede N, Voll RE, Stuchly J, Bakardjieva M, Kalina T, Smulski CR, Venhoff N, Rizzi M. Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis. Ann Rheum Dis. 2024 Jun 8:ard-2024-225587. doi: 10.1136/ard-2024-225587. Epub ahead of print. PMID: 38851295.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38851295/

Kessler S, Burke B, Andrieux G, Schinköthe J, Hamberger L, Kacza J, Zhan S, Reasoner C, Dutt TS, Kaukab Osman M, Henao-Tamayo M, Staniek J, Villena Ossa JF, Frank DT, Ma W, Ulrich R, Cathomen T, Boerries M, Rizzi M, Beer M, Schwemmle M, Reuther P, Schountz T, Ciminski K. Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nat Commun. 2024 May 27;15(1):4500. doi: 10.1038/s41467-024-48934-6. PMID: 38802391; PMCID: PMC11130286.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38802391/

Santos RF, de Sousa Linhares A, Steinberger P, Davis SJ, Oliveira L, Carmo AM. The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling. Cell Commun Signal. 2024 May 24;22(1):286. doi: 10.1186/s12964-024-01658-y. PMID: 38790044; PMCID: PMC11127300.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38790044/

Brunnberg J, Barends M, Frühschulz S, Winter C, Battin C, de Wet B, Cole DK, Steinberger P, Tampé R. Dual role of the peptide-loading complex as proofreader and limiter of MHC-I presentation. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2321600121. doi: 10.1073/pnas.2321600121. Epub 2024 May 21. PMID: 38771881.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38771881/

Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. J Exp Med. 2024 Jul 1;221(7):e20221122. doi: 10.1084/jem.20221122. Epub 2024 May 9. Erratum in: J Exp Med. 2024 Jul 1;221(7): PMID: 38722309; PMCID: PMC11082451.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38722309/

López-Cerdá S, Molinaro G, Tello RP, Correia A, Künig S, Steinberger P, Jeltsch M, Hirvonen JT, Barreto G, Stöckl J, Santos HA. Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid-Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy. ACS Appl Mater Interfaces. 2024 Apr 17;16(15):18643-18657. doi: 10.1021/acsami.4c02363. Epub 2024 Apr 2. PMID: 38564504; PMCID: PMC11040533.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38564504/

Tittes J, Brell J, Fritz P, Jonak C, Stary G, Ressler JM, Künig S, Weninger W, Stöckl J. Regulation of the Immune Cell Repertoire in Psoriasis Patients Upon Blockade of IL-17A or TNFα. Dermatol Ther (Heidelb). 2024 Mar;14(3):613-626. doi: 10.1007/s13555-024-01112-4. Epub 2024 Mar 8. PMID: 38459237; PMCID: PMC10965886.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38459237/

De Sousa Linhares A, Sharma S, Steinberger P, Leitner J. Transcriptional reprogramming via signaling domains of CD2, CD28, and 4-1BB. iScience. 2024 Feb 19;27(3):109267. doi: 10.1016/j.isci.2024.109267. PMID: 38455974; PMCID: PMC10918215.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38455974/

Voogd L, Drittij AMHF, Dingenouts CKE, Franken KLMC, Unen VV, van Meijgaarden KE, Ruibal P, Hagedoorn RS, Leitner JA, Steinberger P, Heemskerk MHM, Davis MM, Scriba TJ, Ottenhoff THM, Joosten SA. Mtb HLA-E-tetramer-sorted CD8⁺ T cells have a diverse TCR repertoire. iScience. 2024 Feb 15;27(3):109233. doi: 10.1016/j.isci.2024.109233. PMID: 38439958; PMCID: PMC10909886.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38439958/

Russo V, Prencipe G, Mauro A, El Khatib M, Haidar-Montes AA, Cambise N, Turriani M, Stöckl J, Steinberger P, Lancia L, Schnabelrauch M, Berardinelli P, Barboni B. Assessing the functional potential of conditioned media derived from amniotic epithelial stem cells engineered on 3D biomimetic scaffolds: An in vitro model for tendon regeneration. Mater Today Bio. 2024 Feb 18;25:101001. doi: 10.1016/j.mtbio.2024.101001. PMID: 38420144; PMCID: PMC10899023.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38420144/

Funk MA, Heller G, Waidhofer-Söllner P, Leitner J, Steinberger P. Inhibitory CARs fail to protect from immediate T cell cytotoxicity. Mol Ther. 2024 Apr 3;32(4):982-999. doi: 10.1016/j.ymthe.2024.02.022. Epub 2024 Feb 22. PMID: 38384128.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38384128/

Sehgal ANA, Safran J, Kratzer B, Gattinger P, Stieger RB, Musiejovsky L, Trapin D, Ettel P, Körmöczi U, Rottal A, Borochova K, Dorofeeva Y, Tulaeva I, Weber M, Grabmeier-Pfistershammer K, Perkmann T, Wiedermann U, Valenta R, Pickl WF. Flow Cytometry-Based Measurement of Antibodies Specific for Cell Surface-Expressed Folded SARS-CoV-2 Receptor-Binding Domains. Vaccines (Basel). 2024 Apr 1;12(4):377. doi: 10.3390/vaccines12040377. PMID: 38675759; PMCID: PMC11053794.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38675759/

Gattinger P, Kratzer B, Sehgal ANA, Ohradanova-Repic A, Gebetsberger L, Tajti G, Focke-Tejkl M, Schaar M, Fuhrmann V, Petrowitsch L, Keller W, Högler S, Stockinger H, Pickl WF, Valenta R. Vaccine Based on Recombinant Fusion Protein Combining Hepatitis B Virus PreS with SARS-CoV-2 Wild-Type- and Omicron-Derived Receptor Binding Domain Strongly Induces Omicron-Neutralizing Antibodies in a Murine Model. Vaccines (Basel). 2024 Feb 23;12(3):229. doi: 10.3390/vaccines12030229. PMID: 38543863; PMCID: PMC10975884.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38543863/

Bojko M, Węgrzyn K, Sikorska E, Ciura P, Battin C, Steinberger P, Magiera-Mularz K, Dubin G, Kulesza A, Sieradzan AK, Spodzieja M, Rodziewicz-Motowidło S. Peptide-based inhibitors targeting the PD-1/PD-L1 axis: potential immunotherapeutics for cancer. Transl Oncol. 2024 Apr;42:101892. doi: 10.1016/j.tranon.2024.101892. Epub 2024 Feb 14. PMID: 38359715; PMCID: PMC10877416.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38359715/

Lippert AH, Paluch C, Gaglioni M, Vuong MT, McColl J, Jenkins E, Fellermeyer M, Clarke J, Sharma S, Moreira da Silva S, Akkaya B, Anzilotti C, Morgan SH, Jessup CF, Körbel M, Gileadi U, Leitner J, Knox R, Chirifu M, Huo J, Yu S, Ashman N, Lui Y, Wilkinson I, Attfield KE, Fugger L, Robertson NJ, Lynch CJ, Murray L, Steinberger P, Santos AM, Lee SF, Cornall RJ, Klenerman D, Davis SJ. Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases. Immunity. 2024 Feb 13;57(2):256-270.e10. doi: 10.1016/j.immuni.2024.01.007. PMID: 38354703.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38354703/

Schaffer AM, Fiala GJ, Hils M, Natali E, Babrak L, Herr LA, Romero-Mulero MC, Cabezas-Wallscheid N, Rizzi M, Miho E, Schamel WWA, Minguet S. Kidins220 regulates the development of B cells bearing the λ light chain. Elife. 2024 Jan 25;13:e83943. doi: 10.7554/eLife.83943. PMID: 38271217; PMCID: PMC10810608.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38271217/

Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, Díez P, Bakardjieva M, Stancikova J, Raabe J, Neumann J, Schwenk S, Arpesella L, Stuchly J, Benes V, García Valiente R, Fernández García J, Carsetti R, Piano Mortari E, Catala A, de la Calle O, Sogkas G, Neven B, Rieux-Laucat F, Magerus A, Neth O, Olbrich P, Voll RE, Alsina L, Allende LM, Gonzalez-Granado LI, Böhler C, Thiel J, Venhoff N, Lorenzetti R, Warnatz K, Unger S, Seidl M, Mielenz D, Schneider P, Ehl S, Rensing-Ehl A, Smulski CR, Rizzi M. Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Sci Immunol. 2024 Jan 12;9(91):eadj5948. doi: 10.1126/sciimmunol.adj5948. Epub 2024 Jan 12. PMID: 38215192.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38215192/

Meyer M, Parpoulas C, Barthélémy T, Becker JP, Charoentong P, Lyu Y, Börsig S, Bulbuc N, Tessmer C, Weinacht L, Ibberson D, Schmidt P, Pipkorn R, Eichmüller SB, Steinberger P, Lindner K, Poschke I, Platten M, Fröhling S, Riemer AB, Hassel JC, Roberti MP, Jäger D, Zörnig I, Momburg F. MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection. Front Immunol. 2024 Jan 4;14:1294565. doi: 10.3389/fimmu.2023.1294565. PMID: 38239352; PMCID: PMC10794645.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38239352/

Michalsen A, Goldenstein K, Kardos P, Klimek L, Palm J, Parganlija D, Stöckl J. The impact of cineole treatment timing on common cold duration and symptoms: Non-randomized exploratory clinical trial. PLoS One. 2024 Jan 18;19(1):e0296482. doi: 10.1371/journal.pone.0296482. PMID: 38236839; PMCID: PMC10795983.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38236839/

Sharma S, Whitehead T, Kotowski M, Ng EZQ, Clarke J, Leitner J, Chen YL, Santos AM, Steinberger P, Davis SJ. A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells. Life Sci Alliance. 2023 Dec 7;7(3):e202302359. doi: 10.26508/lsa.202302359. PMID: 38073578; PMCID: PMC10703992.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38073578/