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2017

Publications 2017

Battin, C., Hennig, A., Mayrhofer, P., Kunert, R., Zlabinger, G. J., Steinberger, P. & Paster, W. A human monocytic NF-kappaB fluorescent reporter cell line for detection of microbial contaminants in biological samples. PLoS One 12, e0178220, doi:10.1371/journal.pone.0178220 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28542462


Colomer-Lahiguera, S., Pisecker, M., Konig, M., Nebral, K., Pickl, W. F., Kauer, M. O., Haas, O. A., Ullmann, R., Attarbaschi, A., Dworzak, M. N. & Strehl, S. MEF2C-dysregulated pediatric T-cell acute lymphoblastic leukemia is associated with CDKN1B deletions and a poor response to glucocorticoid therapy. Leuk Lymphoma 58, 2895-2904, doi:10.1080/10428194.2017.1312383 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28482719


de Bruijn, M. J., Rip, J., van der Ploeg, E. K., van Greuningen, L. W., Ta, V. T., Kil, L. P., Langerak, A. W., Rimmelzwaan, G. F., Ellmeier, W., Hendriks, R. W. & Corneth, O. B. Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling. J Immunol 198, 3058-3068, doi:10.4049/jimmunol.1601285 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28275136


Dillinger, B., Ahmadi-Erber, S., Soukup, K., Halfmann, A., Schrom, S., Vanhove, B., Steinberger, P., Geyeregger, R., Ladisch, S. & Dohnal, A. M. CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity. Front Immunol 8, 1152, doi:10.3389/fimmu.2017.01152 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28979262


Grabmeier-Pfistershammer, K., Stecher, C., Zettl, M., Rosskopf, S., Rieger, A., Zlabinger, G. J. & Steinberger, P. Antibodies targeting BTLA or TIM-3 enhance HIV-1 specific T cell responses in combination with PD-1 blockade. Clin Immunol 183, 167-173, doi:10.1016/j.clim.2017.09.002 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28882621


Jonker, W., Zwart, N., Stockl, J. B., de Koning, S., Schaap, J., Lamoree, M. H., Somsen, G. W., Hamers, T. & Kool, J. Continuous fraction collection of gas chromatographic separations with parallel mass spectrometric detection applied to cell-based bioactivity analysis. Talanta 168, 162-167, doi:10.1016/j.talanta.2017.02.067 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28391837

 

Jurkin, J., Krump, C., Köffel, R., Fieber, C., Schuster, C., Brunner, P. M., Borek, I., Eisenwort, G., Lim, C., Mages, J., Lang, R., Bauer, W., Mechtcheriakova, D., Meshcheryakova, A., Elbe-Bürger, A., Stingl, G., Strobl, H. Human skin dendritic cell fate is differentially regulated by the monocyte identity factor Kruppel-like factor 4 during steady state and inflammation. J Allergy Clin Immunol. 139(6):1873-1884.e10. doi 10.1016/j.jaci.2016.09.018 (2017).
Abstract: https://pubmed.ncbi.nlm.nih.gov/27742396/


Jutz, S., Hennig, A., Paster, W., Asrak, O., Dijanovic, D., Kellner, F., Pickl, W. F., Huppa, J. B., Leitner, J. & Steinberger, P. A cellular platform for the evaluation of immune checkpoint molecules. Oncotarget 8, 64892-64906, doi:10.18632/oncotarget.17615 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29029399


Kovarik, J. J., Kernbauer, E., Holzl, M. A., Hofer, J., Gualdoni, G. A., Schmetterer, K. G., Miftari, F., Sobanov, Y., Meshcheryakova, A., Mechtcheriakova, D., Witzeneder, N., Greiner, G., Ohradanova-Repic, A., Waidhofer-Sollner, P., Saemann, M. D., Decker, T. & Zlabinger, G. J. Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis. PLoS One 12, e0180900, doi:10.1371/journal.pone.0180900 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28742108


Muller, L., Hainberger, D., Stolz, V., Hamminger, P., Hassan, H., Preglej, T., Boucheron, N., Sakaguchi, S., Wiegers, G. J., Villunger, A., Auwerx, J. & Ellmeier, W. The corepressor NCOR1 regulates the survival of single-positive thymocytes. Sci Rep 7, 15928, doi:10.1038/s41598-017-15918-0 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29162920


Nagy, L. & Ellmeier, W. Immunity meets metabolism and then they start talking. FEBS Lett 591, 2957-2958, doi:10.1002/1873-3468.12857 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29023724


Puck, A., Hopf, S., Modak, M., Majdic, O., Cejka, P., Bluml, S., Schmetterer, K., Arnold-Schrauf, C., Gerwien, J. G., Frederiksen, K. S., Thell, E., Leitner, J., Steinberger, P., Aigner, R., Seyerl-Jiresch, M., Zlabinger, G. J. & Stockl, J. The soluble cytoplasmic tail of CD45 (ct-CD45) in human plasma contributes to keep T cells in a quiescent state. Eur J Immunol 47, 193-205, doi:10.1002/eji.201646405 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27718235


Schmetterer, K. G. & Pickl, W. F. The IL-10/STAT3 axis: Contributions to immune tolerance by thymus and peripherally derived regulatory T-cells. Eur J Immunol 47, 1256-1265, doi:10.1002/eji.201646710 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28631311


Schmidt, R. L., Jutz, S., Goldhahn, K., Witzeneder, N., Gerner, M. C., Trapin, D., Greiner, G., Hoermann, G., Steiner, G., Pickl, W. F., Burgmann, H., Steinberger, P., Ratzinger, F. & Schmetterer, K. G. Chloroquine inhibits human CD4(+) T-cell activation by AP-1 signaling modulation. Sci Rep 7, 42191, doi:10.1038/srep42191 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28169350


Selb, R., Eckl-Dorna, J., Neunkirchner, A., Schmetterer, K., Marth, K., Gamper, J., Jahn-Schmid, B., Pickl, W. F., Valenta, R. & Niederberger, V. CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells. J Allergy Clin Immunol 139, 290-299 e294, doi:10.1016/j.jaci.2016.03.042 (2017). Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27372566


Smole, U., Schabussova, I., Pickl, W. F. & Wiedermann, U. Murine models for mucosal tolerance in allergy. Semin Immunol 30, 12-27, doi:10.1016/j.smim.2017.07.007 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28807539


Stecher, C., Battin, C., Leitner, J., Zettl, M., Grabmeier-Pfistershammer, K., Holler, C., Zlabinger, G. J. & Steinberger, P. PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells. Front Immunol 8, 572, doi:10.3389/fimmu.2017.00572 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28588576


Tauber, P. A. & Pickl, W. F. Pharmacological targeting of allergen-specific T lymphocytes. Immunol Lett 189, 27-39, doi:10.1016/j.imlet.2017.03.010 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28322861


Vogl, U. M., Ohler, L., Rasic, M., Frischer, J. M., Modak, M. & Stockl, J. Evaluation of Prognostic Immune Signatures in Patients with Breast, Colorectal and Pancreatic Cancer Receiving Chemotherapy. Anticancer Res 37, 1947-1955, doi:10.21873/anticanres.11535 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28373465


Zulehner, N., Nagl, B., Briza, P., Roulias, A., Ballmer-Weber, B., Zlabinger, G. J., Ferreira, F. & Bohle, B. Characterization of the T-cell response to Dau c 1, the Bet v 1-homolog in carrot. Allergy 72, 244-251, doi:10.1111/all.12938 (2017).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27222434