Publications 2014
Adanitsch, F., Ittig, S., Stockl, J., Oblak, A., Haegman, M., Jerala, R., Beyaert, R., Kosma, P. & Zamyatina, A. Development of alphaGlcN(1<-->1)alphaMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists. J Med Chem 57, 8056-8071, doi:10.1021/jm500946r (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25252784
Boucheron, N., Tschismarov, R., Goeschl, L., Moser, M. A., Lagger, S., Sakaguchi, S., Winter, M., Lenz, F., Vitko, D., Breitwieser, F. P., Muller, L., Hassan, H., Bennett, K. L., Colinge, J., Schreiner, W., Egawa, T., Taniuchi, I., Matthias, P., Seiser, C. & Ellmeier, W. CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. Nat Immunol 15, 439-448, doi:10.1038/ni.2864 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24681565
Cerny-Reiterer, S., Meyer, R. A., Herrmann, H., Peter, B., Gleixner, K. V., Stefanzl, G., Hadzijusufovic, E., Pickl, W. F., Sperr, W. R., Melo, J. V., Maeda, H., Jager, U. & Valent, P. Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia. Oncotarget 5, 1198-1211, doi:10.18632/oncotarget.1805 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24681707
Deifl, S., Zwicker, C., Vejvar, E., Kitzmuller, C., Gadermaier, G., Nagl, B., Vrtala, S., Briza, P., Zlabinger, G. J., Jahn-Schmid, B., Ferreira, F. & Bohle, B. Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen. PLoS One 9, e109075, doi:10.1371/journal.pone.0109075 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25275548
Deifl, S., Kitzmuller, C., Steinberger, P., Himly, M., Jahn-Schmid, B., Fischer, G. F., Zlabinger, G. J. & Bohle, B. Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naive CD4+ T cells from allergic patients. Allergy 69, 1602-1609, doi:10.1111/all.12501 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25093709
Ellmeier, W. & Taniuchi, I. The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity. Curr Top Microbiol Immunol 381, 21-49, doi:10.1007/82_2014_374 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24850219
Eskandary, F., Wahrmann, M., Biesenbach, P., Sandurkov, C., Konig, F., Schwaiger, E., Perkmann, T., Kunig, S., Derfler, K., Zlabinger, G. J. & Bohmig, G. A. ABO antibody and complement depletion by immunoadsorption combined with membrane filtration--a randomized, controlled, cross-over trial. Nephrol Dial Transplant 29, 706-714, doi:10.1093/ndt/gft502 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24378525
Forster, F., Paster, W., Supper, V., Schatzlmaier, P., Sunzenauer, S., Ostler, N., Saliba, A., Eckerstorfer, P., Britzen-Laurent, N., Schutz, G., Schmid, J. A., Zlabinger, G. J., Naschberger, E., Sturzl, M. & Stockinger, H. Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton. J Immunol 192, 771-781, doi:10.4049/jimmunol.1300377 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24337748
Gualdoni, G. A., Kovarik, J. J., Hofer, J., Dose, F., Pignitter, M., Doberer, D., Steinberger, P., Somoza, V., Wolzt, M. & Zlabinger, G. J. Resveratrol enhances TNF-alpha production in human monocytes upon bacterial stimulation. Biochim Biophys Acta 1840, 95-105, doi:10.1016/j.bbagen.2013.09.009 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24035785
Kikic, Z., Kozakowski, N., Regele, H., Priessner, K., Nordmeyer, V., Marinova, L., Zlabinger, G. J., Wahrmann, M., Bartel, G. & Bohmig, G. A. Clinicopathological relevance of granular C4d deposition in peritubular capillaries of kidney allografts. Transpl Int 27, 312-321, doi:10.1111/tri.12254 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24299498
Köffel, R., Meshcheryakova, A., Warszawska, J., Hennig, A., Wagner, K., Jörgl, A., Gubi, D., Moser, D., Hladik, A., Hoffmann, U., Fischer, M.B., van den Berg, W., Koenders, M., Scheinecker, C., Gesslbauer, B., Knapp, S., Strobl, H. Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. Blood. 124(17):2713-24. doi: 10.1182/blood-2014-07-588178. (2014)
Abstract: https://pubmed.ncbi.nlm.nih.gov/25214442/
Konradi, S., Yasmin, N., Haslwanter, D., Weber, M., Gesslbauer, B., Sixt, M., Strobl, H. Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2. Eur J Immunol. 44(2):553-60. doi: 0.1002/eji.201343681. (2014)
Abstract: https://pubmed.ncbi.nlm.nih.gov/24165969/
Maurer, M., Muller, A. C., Parapatics, K., Pickl, W. F., Wagner, C., Rudashevskaya, E. L., Breitwieser, F. P., Colinge, J., Garg, K., Griss, J., Bennett, K. L. & Wagner, S. N. Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma. J Proteome Res 13, 2830-2845, doi:10.1021/pr401270y (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24803318
Neunkirchner, A., Schmetterer, K. G. & Pickl, W. F. Lymphocyte-based model systems for allergy research: a historic overview. Int Arch Allergy Immunol 163, 259-291, doi:10.1159/000360163 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24777172
Peter, B., Cerny-Reiterer, S., Hadzijusufovic, E., Schuch, K., Stefanzl, G., Eisenwort, G., Gleixner, K. V., Hoermann, G., Mayerhofer, M., Kundi, M., Baumgartner, S., Sperr, W. R., Pickl, W. F., Willmann, M. & Valent, P. The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells. J Leukoc Biol 95, 95-104, doi:10.1189/jlb.1112609 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24052572
Popow, I. & Steinberger, P. HLA antibodies in ATGs. Am J Transplant 14, 738, doi:10.1111/ajt.12621 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24447720
Ratzinger, F., Haslacher, H., Poeppl, W., Hoermann, G., Kovarik, J. J., Jutz, S., Steinberger, P., Burgmann, H., Pickl, W. F. & Schmetterer, K. G. Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. Sci Rep 4, 7438, doi:10.1038/srep07438 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25500904
Reitter, E. M., Ay, C., Kaider, A., Pirker, R., Zielinski, C., Zlabinger, G. & Pabinger, I. Interleukin levels and their potential association with venous thromboembolism and survival in cancer patients. Clin Exp Immunol 177, 253-260, doi:10.1111/cei.12308 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24580121
Salzer, E., Kansu, A., Sic, H., Majek, P., Ikinciogullari, A., Dogu, F. E., Prengemann, N. K., Santos-Valente, E., Pickl, W. F., Bilic, I., Ban, S. A., Kuloglu, Z., Demir, A. M., Ensari, A., Colinge, J., Rizzi, M., Eibel, H. & Boztug, K. Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency. J Allergy Clin Immunol 133, 1651-1659 e1612, doi:10.1016/j.jaci.2014.02.034 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24746753
Seidel, M. G., Duerr, C., Woutsas, S., Schwerin-Nagel, A., Sadeghi, K., Neesen, J., Uhrig, S., Santos-Valente, E., Pickl, W. F., Schwinger, W., Urban, C., Boztug, K. & Forster-Waldl, E. A novel immunodeficiency syndrome associated with partial trisomy 19p13. J Med Genet 51, 254-263, doi:10.1136/jmedgenet-2013-102122 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24431329
Seltenhammer, M. H., Sundstrom, E., Meisslitzer-Ruppitsch, C., Cejka, P., Kosiuk, J., Neumuller, J., Almeder, M., Majdic, O., Steinberger, P., Losert, U. M., Stockl, J., Andersson, L., Solkner, J., Vetterlein, M. & Golovko, A. Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses. In Vitro Cell Dev Biol Anim 50, 56-65, doi:10.1007/s11626-013-9678-1 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23982913
Strobl, H. Inflammatory Langerhans cell differentiation. Blood. 124(15):2319-20.doi: 10.1182/blood-2014-08-597096. (2014).
Abstract: https://pubmed.ncbi.nlm.nih.gov/25301332/
Tschismarov, R., Firner, S., Gil-Cruz, C., Goschl, L., Boucheron, N., Steiner, G., Matthias, P., Seiser, C., Ludewig, B. & Ellmeier, W. HDAC1 controls CD8+ T cell homeostasis and antiviral response. PLoS One 9, e110576, doi:10.1371/journal.pone.0110576 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25333902
Willmann, K. L., Klaver, S., Dogu, F., Santos-Valente, E., Garncarz, W., Bilic, I., Mace, E., Salzer, E., Conde, C. D., Sic, H., Majek, P., Banerjee, P. P., Vladimer, G. I., Haskologlu, S., Bolkent, M. G., Kupesiz, A., Condino-Neto, A., Colinge, J., Superti-Furga, G., Pickl, W. F., van Zelm, M. C., Eibel, H., Orange, J. S., Ikinciogullari, A. & Boztug, K. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun 5, 5360, doi:10.1038/ncomms6360 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25406581
Zwolanek, F., Riedelberger, M., Stolz, V., Jenull, S., Istel, F., Koprulu, A. D., Ellmeier, W. & Kuchler, K. The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome. PLoS Pathog 10, e1004525, doi:10.1371/journal.ppat.1004525 (2014).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25474208