Publications 2018
Crncec, I., Modak, M., Gordziel, C., Svinka, J., Scharf, I., Moritsch, S., Pathria, P., Schlederer, M., Kenner, L., Timelthaler, G., Muller, M., Strobl, B., Casanova, E., Bayer, E., Mohr, T., Stockl, J., Friedrich, K. & Eferl, R. STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer. Mol Oncol 12, 514-528, doi:10.1002/1878-0261.12178 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29419930
De Sousa Linhares, A., Leitner, J., Grabmeier-Pfistershammer, K. & Steinberger, P. Not All Immune Checkpoints Are Created Equal. Front Immunol 9, 1909, doi:10.3389/fimmu.2018.01909 (2018). Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30233564
Ellmeier, W. & Seiser, C. Histone deacetylase function in CD4(+) T cells. Nat Rev Immunol 18, 617-634, doi:10.1038/s41577-018-0037-z (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30022149
Garner-Spitzer, E., Seidl-Friedrich, C., Zwazl, I., Hofer, M., Kinaciyan, T., Jarisch, R., Stiasny, K., Zlabinger, G. J., Kundi, M. & Wiedermann, U. Allergic patients with and without allergen-specific immunotherapy mount protective immune responses to tick-borne encephalitis vaccination in absence of enhanced side effects or propagation of their Th2 bias. Vaccine 36, 2816-2824, doi:10.1016/j.vaccine.2018.03.076 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29673942
Goschl, L., Preglej, T., Hamminger, P., Bonelli, M., Andersen, L., Boucheron, N., Gulich, A. F., Muller, L., Saferding, V., Mufazalov, I. A., Hirahara, K., Seiser, C., Matthias, P., Penz, T., Schuster, M., Bock, C., Waisman, A., Steiner, G. & Ellmeier, W. A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. J Autoimmun 86, 51-61, doi:10.1016/j.jaut.2017.09.008 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28964722
Gualdoni, G. A., Mayer, K. A., Kapsch, A. M., Kreuzberg, K., Puck, A., Kienzl, P., Oberndorfer, F., Fruhwirth, K., Winkler, S., Blaas, D., Zlabinger, G. J. & Stockl, J. Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication. Proc Natl Acad Sci U S A 115, E7158-E7165, doi:10.1073/pnas.1800525115 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29987044
Hecht, I., Toporik, A., Podojil, J. R., Vaknin, I., Cojocaru, G., Oren, A., Aizman, E., Liang, S. C., Leung, L., Dicken, Y., Novik, A., Marbach-Bar, N., Elmesmari, A., Tange, C., Gilmour, A., McIntyre, D., Kurowska-Stolarska, M., McNamee, K., Leitner, J., Greenwald, S., Dassa, L., Levine, Z., Steinberger, P., Williams, R. O., Miller, S. D., McInnes, I. B., Neria, E. & Rotman, G. ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses. J Immunol 200, 2025-2037, doi:10.4049/jimmunol.1700325 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29431694
Jaeger-Lansky, A., Schmidthaler, K., Kuessel, L., Gstottner, M., Waidhofer-Sollner, P., Zlabinger, G. J., Wenzl, R. & Eiwegger, T. Local and systemic levels of cytokines and danger signals in endometriosis-affected women. J Reprod Immunol 130, 7-10, doi:10.1016/j.jri.2018.07.006 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30099220
Kitzmuller, C., Kalser, J., Mutschlechner, S., Hauser, M., Zlabinger, G. J., Ferreira, F. & Bohle, B. Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity, reduced allergenicity, and intrinsic adjuvanticity. J Allergy Clin Immunol 141, 293-299 e296, doi:10.1016/j.jaci.2017.02.044 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28456624
Muller, L., Hainberger, D., Stolz, V. & Ellmeier, W. NCOR1-a new player on the field of T cell development. J Leukoc Biol 104, 1061-1068, doi:10.1002/JLB.1RI0418-168R (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30117609
Neunkirchner, A., Kratzer, B., Kohler, C., Smole, U., Mager, L. F., Schmetterer, K. G., Trapin, D., Leb-Reichl, V., Rosloniec, E., Naumann, R., Kenner, L., Jahn-Schmid, B., Bohle, B., Valenta, R. & Pickl, W. F. Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice. EBioMedicine 31, 66-78, doi:10.1016/j.ebiom.2018.04.001 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29678672
Ohradanova-Repic, A., Machacek, C., Charvet, C., Lager, F., Le Roux, D., Platzer, R., Leksa, V., Mitulovic, G., Burkard, T. R., Zlabinger, G. J., Fischer, M. B., Feuillet, V., Renault, G., Bluml, S., Benko, M., Suchanek, M., Huppa, J. B., Matsuyama, T., Cavaco-Paulo, A., Bismuth, G. & Stockinger, H. Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances. Front Immunol 9, 852, doi:10.3389/fimmu.2018.00852 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29780382
Pablos, I., Eichhorn, S., Machado, Y., Briza, P., Neunkirchner, A., Jahn-Schmid, B., Wildner, S., Soh, W. T., Ebner, C., Park, J. W., Pickl, W. F., Arora, N., Vieths, S., Ferreira, F. & Gadermaier, G. Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity. Allergy 73, 431-441, doi:10.1111/all.13298 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28960341
Rosskopf, S., Leitner, J., Paster, W., Morton, L. T., Hagedoorn, R. S., Steinberger, P. & Heemskerk, M. H. M. A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies. Oncotarget 9, 17608-17619, doi:10.18632/oncotarget.24807 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29707134
Rosskopf, S., Jahn-Schmid, B., Schmetterer, K. G., Zlabinger, G. J. & Steinberger, P. PD-1 has a unique capacity to inhibit allergen-specific human CD4(+) T cell responses. Sci Rep 8, 13543, doi:10.1038/s41598-018-31757-z (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30201974
Schmid, N., Stockl, J. B., Flenkenthaler, F., Dietrich, K. G., Schwarzer, J. U., Kohn, F. M., Drummer, C., Frohlich, T., Arnold, G. J., Behr, R. & Mayerhofer, A. Characterization of a non-human primate model for the study of testicular peritubular cells-comparison with human testicular peritubular cells. Mol Hum Reprod 24, 401-410, doi:10.1093/molehr/gay025 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29846669
Skrabs, C., Pickl, W. F., Perkmann, T., Jager, U. & Gessl, A. Rapid decline in insulin antibodies and glutamic acid decarboxylase autoantibodies with ibrutinib therapy of chronic lymphocytic leukaemia. J Clin Pharm Ther 43, 145-149, doi:10.1111/jcpt.12602 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28753229
Valenta, R., Karaulov, A., Niederberger, V., Gattinger, P., van Hage, M., Flicker, S., Linhart, B., Campana, R., Focke-Tejkl, M., Curin, M., Eckl-Dorna, J., Lupinek, C., Resch-Marat, Y., Vrtala, S., Mittermann, I., Garib, V., Khaitov, M., Valent, P. & Pickl, W. F. Molecular Aspects of Allergens and Allergy. Adv Immunol 138, 195-256, doi:10.1016/bs.ai.2018.03.002 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29731005
Vizzardelli, C., Gindl, M., Roos, S., Mobs, C., Nagl, B., Zimmann, F., Sexl, V., Kenner, L., Neunkirchner, A., Zlabinger, G. J., Pickl, W. F., Pfutzner, W. & Bohle, B. Blocking antibodies induced by allergen-specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model. Allergy 73, 851-861, doi:10.1111/all.13363 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29159964
Weinhofer, I., Zierfuss, B., Hametner, S., Wagner, M., Popitsch, N., Machacek, C., Bartolini, B., Zlabinger, G., Ohradanova-Repic, A., Stockinger, H., Kohler, W., Hoftberger, R., Regelsberger, G., Forss-Petter, S., Lassmann, H. & Berger, J. Impaired plasticity of macrophages in X-linked adrenoleukodystrophy. Brain 141, 2329-2342, doi:10.1093/brain/awy127 (2018).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29860501