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AG Tumorpathologie

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Arbeitsgruppe Tumorpathologie

Ziel der Forschungsgruppe Tumorpathologie ist es, zelluläre und molekulare Mechanismen zu verstehen und aufzudecken, die bei der Prävention und Pathogenese von Darmkrebs und anderen chronischen oder bösartigen Erkrankungen eine Rolle spielen. In diesem Prozess untersuchen wir auch die Rolle von Vitamin D und Kalzium in der Nahrung .

Eine weitere Hauptaufgabe besteht darin, Student:innen vor und nach dem Studium zu hervorragenden Wissenschaftler:innen in der biologischen und experimentellen medizinischen Forschung auszubilden.

Interessent:innen für Bachelor- oder Masterarbeiten bitte bei Dr. Schepelmann bewerben: martin.schepelmann@meduniwien.ac.at.

Derzeitige Forschungsschwerpunkte:

  1. Untersuchen von kalziumabhängigen molekularen Antitumormechanismen
  2. Rolle des Calcium-Sensing-Rezeptors (CaSR) bei der kolorektalen Karzinogenese
  3. Identifizieren von genetischen und epigenetischen Mechanismen, die die Wirkung von Kalzium und Vitamin D bei der Tumorentstehung regulieren
  4. Untersuchen des Vitamin-D-Systems als physiologische Abwehr gegen die Tumorprogression
  5. Einfluss des Vitamin-D-abbauenden Enzyms 25-Hydroxyvitamin-D-24-Hydroxylase auf die Kolontumorentstehung
  6. Orts- und geschlechtsspezifische Entwicklung von kolorektalen Tumoren
  • 2017 - 2022
    Austrian Science Fond, Prj. Nr.: P 29948 - B28, Loss of the CaSR in colorectal tumorgenesis
  • 2016 - 2020
    European Community: Horizon 2020 Proj. No. 675228: The Calcium Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases (CaSR Biomedicine), funded under the Marie-Skłodowska Curie Actions as a European Training Network
  • 2014 - 2017
    Austrian Science Fond, Proj.Nr.: I 1662-B13, Ca2+ signalling in BRAF mutant tumors: therapeutic resistance and drug combinations
  • 2013 - 2017
    Vienna Science and Technology Fund (WWTF) LS12-047: Dietary vitamin D, a powerful weapon in the war against colorectal cancer
  • 2011 - 2014
    European Community: FP7-264663 The role of the Calcium Sensing Receptor (CaSR) in health and disease, implications for translational medicine
  • 2010 - 2012
    Herzfeldersche Familienstiftung: Is the calcium sensing receptor a tumour suppressor in colorectal cancer
  • 2009 - 2013
    Austrian Science Fond, P22200: Is the vitamin D catabolising enzyme CYP24A1 an oncogene
  • 2007 - 2008
    European Community: MEIF-CT-2007-041276: Marie Curie Inter European Fellowship (EU): Calcium sensing receptor in colon cancer
  • 2006 - 2009
    European Community: MRTN-CT-2005-019496: Research Training Network NUCSYS: Systems Biology of Nuclear Receptors: A Nutrigenomic Approach to Aging-Related Diseases
  • 2002 - 2004
    Austrian National Bank, Project # 9335: Oral calcium and colorectal cancer prevention: mechanisms of action in an animal model
  • 2019 Travel Grant awarded to Luca Iamartino from the Österreichische Forschungsgemeinschaft to attend the Conference "Advances in Biomedical research III", Split, June 2019.
  • 2019 Travel Grant awarded to Martin Schepelmann from the Österreichische Forschungsgesellschaft to attend the 22nd Vit-D Workshop in New York, June 2019.
  • 2019 Science Award from the Austrian Society of Endocrinology and Metabolism awarded to Martin Schepelmann.
  • 2019 Mentoring Award from the Austrian Society of Endocrinology and Metabolism awarded to Martin Schepelmann.
  • 2018 Junior Travel Fellowship from the European Calcium Society  awarded to Luca Iamartino to attend the 15th International Meeting, Hamburg, September 2018
  • 2018 Travel Grant from the Comprehensive Cancer Center awarded to Luca Iamartino to attend the 25th Biennal Congress of the European Association for Cancer Research in Amsterdam, July 2018.
  • 2018 Trainee Travel Award from the 21st Workshop on Vit-D awarded to Luca Iamartino.
  • 2018 Young Investigator Award from the Austrian Society of Endocrinology and Metabolism awarded to Martin Schepelmann.
  • 2018 Science Award awarded by the Austrian Society of Endocrinology and Metabolism to Martin Schepelmann, 5-6 April 2018, Linz.
  • 2017 European Association for Cancer Research Travel Fellowship awarded to Luca Iamartino for a research visit to the Instituto de Investigaciones Biomédicas "Alberto Sols", Spain.
  • 2017 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology, Vienna, 19th September 2017, awarded to Malgorzata Cichon.
  • 2016 Comprehensive Cancer Center Travel Grant to attend the Annual Meeting of the American Association for Cancer Research in New Orleans, 16-20 April 2016, awarded to Luca Hegedüs.
  • 2015 Young Investigator Award from the Austrian Society of Endocrinology and Metabolism awarded to Abhishek Aggarwal, Innsbruck, Austria.
  • 2015 Young Investigator Award at the 2nd International Symposium on the Calcium-sensing Receptor awarded to Abhishek Aggarwal, San Diego, USA.
  • 2015 Young Investigator Award at the 2nd International Symposium on the Calcium-sensing Receptor awarded to Samawansha Tennakoon, San Diego, USA.
  • 2015 Travel grant from Österreichischen Forschungsgemeinschaft (ÖFG) awarded to Charlotte Gröschel to participate at the 18th Vitamin D Workshop in Delft, The Netherlands.
  • 2014 Drabikowski Award for the Best Young Speaker awarded to Abhishek Aggarwal at the 13th International Meeting of the European Calcium Society in Aix-en- Provence, France. 
  • 2014 Young Investigator Award from the Austrian Society for Endocrinology and Metabolism awarded to Abhishek Aggarwal, Vienna, 3rd April 2014.
  • 2014 Travel Fellowship from the European Association for Cancer Research for an academic exchange with the University of Cardiff, UK, awarded to Abhishek Aggarwal.
  • 2014 Travel Fellowship from the Austrian Research Academy to attend the Cancer epigenetics/transcriptional regulation meeting in Santa Fe, USA, 4-9 February 2014, awarded to Irfete Fetahu.
  • 2014 Travel Fellowship from the European Association for Cancer Research for a research visit to the University of Oxford, UK, awarded to Irfete Fetahu.
  • 2014 Travel Grant from the Comprehensive Cancer Center  to attend the 17th Workshop on Vitamin D in Chicago, IL, USA, June 17-20, 2014, awarded to Charlotte Gröschel.
  • 2014 Poster Prize at the ÖGKM Austrian Society for Bone and Mineral Research during the Annual Meeting of the ÖGKM awarded to Samawansha Tennakoon,  in Vienna.
  • 2014 Travel Fellowship from the European Association for Cancer Research for an academic exchange with the University of Cardiff, UK, awarded to Samawansha Tennakoon.
  • 2014 Travel Grant from the Austrian Society for Bone and Mineral Metabolism to attend the 13th International Meeting of the European Calcium Society, in Aix-en-Provence, France awarded to Samawansha Tennakoon.
  • 2013 Early Stage Investigator Award from the Austrian Association of Molecular Life Sciences awarded to Abhishek Aggarwal.
  • 2013 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology, Vienna, 17th September 2013, awarded to Abhishek Aggarwal.
  • 2013 Bursary from TransVIr Winter School to attend "Histology and Histopathology" course awarded to Abhishek Aggarwal. 
  • 2013 Travel Stipend from the Austrian Society for Bone and Mineral Research to attend the Annual Meeting of the American Association for Cancer Research in Washington D.C., 6-10 April 2013, awarded to Abhishek Aggarwal.
  • 2013 FEBS Youth Travel Fund from the Federation of Biochemical Societies awarded to Irfete Fetahu to attend the workshop on: "Translating epigenomes to function: a next generation challenge to human disease" in Capri, Italy, 13-16 October 2013.
  • 2013 Young Investigator Award by the Austrian Society for Endocrinology and Metabolism awarded to Irfete Fetahu, Linz, 18-19 April 2013.
  • 2013 Young Scientist Travel Award to attend the cell Symposia on Cancer Epigenomics in Melia, Spain, 6-8 October 2013, awarded by the Comprehensive Cancer Center to Irfete Fetahu.
  • 2013 Travel Fellowship from the Austrian Society for Bone and Mineral Research to attend the Annual Meeting of the American Association for Cancer Research in Washington D.C., 6-10 April 2013, awarded to Irfete Fetahu.
  • 2013 Bursary from TransVIr Winter School to attend "Histology and Histopathology" course awarded to Irfete Fetahu.
  • 2013 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology awarded to Charlotte Gröschel, Vienna, 17th September 2013.
  • 2013 Travel Stipend from the Austrian Society for Bone and Mineral Research to attend the Annual Meeting of the American Association for Cancer Research in Washington D.C., 6-10 April 2013, awarded to Julia Höbaus.
  • 2013 Travel Stipend from the Austrian Research Foundation to attend the Annual Meeting of the American Association for Research Cancer in Washington D.C., 6-10 April 2013, awarded to Julia Höbaus.
  • 2013 Comprehensive Cancer Center Travel Grant to attend the Annual Meeting of the American Association for Cancer Research in Washington D.C., 6-10 April 2013, awarded to Doris Hummel.
  • 2013 Comprehensive Cancer Center Travel Grant to attend the Annual Meeting of the American Association for Cancer Research in Washington D.C., 6-10 April 2013, awarded to Samawansha Tennakoon.
  • 2012 Rote Pfote Science Communication Award 2012 awarded to Abhishek Aggarwal, Vienna, May 2013.
  • 2012 Best Abstract Prize -Travel Award 2012 awarded to Abhishek Aggarwal at the International Conference on Stem Cell and Cancer in New Dehli, India, 27-30 October 2012.
  • 2012 Best Oral Presentation Award at the International Conference on Stem Cell and Cancer in New Dehli, India, 27-30 October 2012, awarded to Abhishek Aggarwal.
  • 2012 Fellowship awarded by the European Calcium Society to Abhishek Aggarwal to facilitate attendance at the ECS meeting in Toulouse, 8-12 September 2012.
  • 2012 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology awarded to Irfete Fetahu on 27th September 2012.
  • 2012 Travel Stipend from the Austrian Society for Bone and Mineral Research to attend the 12th Symposium of the European Calcium Society in Toulouse, 8-10 September 2012, awarded to Irfete Fetahu.
  • 2012 Young Investigator Award from the Austrian Society for Endocrinology and Metabolism to Irfete Fetahu, Graz, 19-20 April 2012.
  • 2012 Travel Grant from the Austrian Research Foundation to attend the 15th Vitamin D Worshop in Houston, USA, 19-23 June 2012,  to Julia Höbaus.
  • 2012 Young Investigator Award received at the 15th Vitamin D Workshop in Houston, USA, 19-23 June 2013, to Julia Höbaus.
  • 2012 Felix Bronner Dissertation Stipend awarded by the Austrian Society of Bone and Mineral Research to Julia Höbaus, St. Wolfgang, 10-12 Mai 2012.
  • 2012 Poster Prize awarded by the Austrian Society of Endocrinology to Julia Höbaus, Graz, 19-20 April 2012.
  • 2012 Science Award awarded by the Austrian Society of Endocrinology to Julia Höbaus, Graz, 19-20 April 2012.
  • 2012 Travel Grant from Böhringer Ingelheim Fond for Research stay at the University of Eastern Finland, Kuopio to Doris Hummel
  • 2012 Young Investigator Award from the Austrian Society of Endocrinology and Metabolism to Doris Hummel, Graz, 19-20 April 2012.
  • 2012 Mentoring Award from Barbara Obermayer- Pietsch from the Austrian Society of Endocrinology and Metabolism to Doris Hummel.
  • 2012 Travel Stipend from the Austrian Society for Bone and Mineral Research to attend the 15th Vitamin D Workshop in Houston, USA, 19-23 June 2013, awarded to Doris Hummel.
  • 2012 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology awarded to Doris Hummel, 27th September 2012.
  • 2011 Poster Prize at the Retreat of the Center of Pathophysiology, Infectiology and Immunology to Julia Höbaus, 27th September 2011.
  • 2011 Travel Grant for presentation at the Annual Meeting of the Austrian Society of Endocrinology in Wien, Austria to Julia Höbaus, Wien, 12-13 Mai 2011.
  • 2011 Travel Grant to attend the Annual Meeting of the American Association for Cancer Research in Orlando, USA, 2-6 April 2011, awarded by the Comprehensive Cancer Center, Medical University of Vienna, to Julia Höbaus.
© Matern, MedUni Wien

Assoc. Prof.in Univ.-Doz.in Mag.a Dr.in Enikö Kallay

Arbeitsgruppenleiterin

Tel.: +43 (0)1 40400-51230
E-Mail: enikoe.kallay@meduniwien.ac.at
Publikationen

Team

ARin Ing.in, CTA
Comparative Immunologie und Onkologie
Labormanagerin
Tel.: +43 (0)1 40400-51290
E-Mail: teresa.manhardt@meduniwien.ac.at

MSc
Comparative Immunologie und Onkologie
Tel.: +43 (0)1 40400-51290
E-Mail: karina.piatek@meduniwien.ac.at

Publikationen

zu den Publikationen
  • Dr. Martin Schepelmann
  • Sarah Guttmann
  • Nadja Kupper, BSc
  • Valeriya Gushchina, BSc Student
  • Katharina Gall, Diploma StudentMSc.
  • Luca Iamartino, PhD Student
  • MSc. Taha Elajnaf, PhD Student
  • Dott.ssa Maria Elena Manfredini, Project Manager
  • BSc. Judit Repas, Master Student
  • BSc. Himadri Bahadur Thapa, Master Student
  • BSc. Malgorzata Cichon, Master Student
  • BSc Nora Geißler, Master Student
  • Bsc. Rebecca Grüneis, Master Student
  • Mag. Maximilian Wohlgenannt, Research Fellow
  • MSc. Luca Hegedüs, PhD Student
  • Dr. Charlotte Gröschel, PhD Student
  • MSc. Samawansha Tennakoon, PhD Student
  • MSc. Abhishek Aggarwal, PhD Student
  • Dr. Giovanna Bises, senior scientist
  • Dr. Ursula Thiem, PhD Student
  • Mag. Doris Hummel, PhD Student
  • Mag. Julia Höbaus, PhD Student
  • MPharm Irfete Fetahu, PhD Student